Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture

Author:

Fisher Matthew C.1ORCID,Gurr Sarah J.2,Cuomo Christina A.3ORCID,Blehert David S.4,Jin Hailing5,Stukenbrock Eva H.67,Stajich Jason E.5ORCID,Kahmann Regine8,Boone Charles91011,Denning David W.12,Gow Neil A. R.2ORCID,Klein Bruce S.13,Kronstad James W.14ORCID,Sheppard Donald C.15,Taylor John W.16,Wright Gerard D.17,Heitman Joseph18,Casadevall Arturo19ORCID,Cowen Leah E.9

Affiliation:

1. MRC Centre for Global Infectious Disease Analysis, Imperial College, London, United Kingdom

2. Department of Biosciences, University of Exeter, Exeter, United Kingdom

3. Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA

4. U.S. Geological Survey, National Wildlife Health Center, Madison, Wisconsin, USA

5. Department of Microbiology and Plant Pathology, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of California—Riverside, Riverside, California, USA

6. Max Planck Fellow Group Environmental Genomics, Max Planck Institute for Evolutionary Biology, Plön, Germany

7. Environmental Genomics, Christian-Albrechts University, Kiel, Germany

8. Max Planck Institute for Terrestrial Microbiology, Department of Organismic Interactions, Marburg, Germany

9. Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

10. The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada

11. RIKEN Center for Sustainable Resource Science, Wako, Saitama, Japan

12. The National Aspergillosis Centre, Wythenshawe Hospital, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

13. Department of Pediatrics, Department of Internal Medicine, and Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin—Madison, Madison, Wisconsin, USA

14. Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

15. McGill Interdisciplinary Initiative in Infection and Immunology, Departments of Medicine, Microbiology & Immunology, McGill University, Montreal, Canada

16. University of California—Berkeley, Department of Plant and Microbial Biology, Berkeley, California, USA

17. M.G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada

18. Department of Molecular Genetics and Microbiology, Medicine, and Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA

19. Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

Abstract

The fungal kingdom includes at least 6 million eukaryotic species and is remarkable with respect to its profound impact on global health, biodiversity, ecology, agriculture, manufacturing, and biomedical research. Approximately 625 fungal species have been reported to infect vertebrates, 200 of which can be human associated, either as commensals and members of our microbiome or as pathogens that cause infectious diseases. These organisms pose a growing threat to human health with the global increase in the incidence of invasive fungal infections, prevalence of fungal allergy, and the evolution of fungal pathogens resistant to some or all current classes of antifungals.

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Cited by 327 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3