Analysis of mRNA Decay Intermediates in Bacillus subtilis 3′ Exoribonuclease and RNA Helicase Mutant Strains-Reference-Cited by-同舟云学术

Analysis of mRNA Decay Intermediates in Bacillus subtilis 3′ Exoribonuclease and RNA Helicase Mutant Strains

Published:2022-04-26 Issue:2 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Chhabra Shivani¹,Mandell Zachary F.²,Liu Bo¹,Babitzke Paul²^ORCID,Bechhofer David H.¹

Affiliation:

1. Icahn School of Medicine at Mount Sinai, Department of Pharmacological Sciences, New York, New York, USA

2. The Pennsylvania State University, Department of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, University Park, Pennsylvania, USA

Abstract

The ability to rapidly change bacterial gene expression programs in response to environmental conditions is highly dependent on the efficient turnover of mRNA. While much is known about the regulation of gene expression at the transcriptional and translational levels, much less is known about the intermediate step of mRNA decay.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00400-22

Reference49 articles.

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3. Initiation of Decay of Bacillus subtilis rpsO mRNA by Endoribonuclease RNase Y