Human Rhinovirus B and C Genomes from Rural Coastal Kenya

Author:

Agoti Charles N.12,Kiyuka Patience K.1,Kamau Everlyn1,Munywoki Patrick K.12,Bett Anne1,van der Hoek Lia3,Kellam Paul45,Nokes D. James16,Cotten Matthew7

Affiliation:

1. Epidemiology and Demography Department, KEMRI—Wellcome Trust Research Programme, Kilifi, Kenya

2. School of Health and Human Sciences, Pwani University, Kilifi, Kenya

3. Laboratory of Experimental Virology, Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands

4. Imperial College London, London, United Kingdom

5. KyMab Limited, Cambridge, United Kingdom

6. School of Life Sciences and WIDER, University of Warwick, Coventry, United Kingdom

7. The Wellcome Trust Sanger Institute, Cambridge, United Kingdom

Abstract

ABSTRACT Primer-independent agnostic deep sequencing was used to generate three human rhinovirus (HRV) B genomes and one HRV C genome from samples collected in a household respiratory survey in rural coastal Kenya. The study provides the first rhinovirus genomes from Kenya and will help improve the sensitivity of local molecular diagnostics.

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

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