Chromosome and Plasmids of the Tick-Borne Relapsing Fever Agent Borrelia hermsii-Reference-Cited by-同舟云学术

Chromosome and Plasmids of the Tick-Borne Relapsing Fever Agent Borrelia hermsii

Published:2016-06-30 Issue:3 Volume:4 Page:
ISSN:2169-8287
Container-title:Genome Announcements
language:en
Short-container-title:Genome Announc

Author:

Barbour Alan G.¹^ORCID

Affiliation:

1. Departments of Microbiology & Molecular Genetics, Medicine, and Ecology & Evolutionary Biology, University of California Irvine, Irvine, California, USA

Abstract

ABSTRACT The zoonotic pathogen Borrelia hermsii bears its multiple paralogous genes for variable antigens on several linear plasmids. Application of combined long-read and short-read next-generation sequencing provided complete sequences for antigen-encoding plasmids as well as other linear and circular plasmids and the linear chromosome of the genome.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/genomeA.00528-16

Reference10 articles.

1. Barbour AG. 2015. Relapsing fever, p. 1146–1149. In Kasper DL, Fauci A, Hauser S, Longo DL, Jameson JL, Loscalzo J (ed), Harrison's principle of internal medicine, 19th ed. McGraw-Hill, New York, NY.

2. Barbour AG, Guo BP. 2010. The pathogenesis of relapsing fever, p. 333–358. In Radolf JD, Samuels DS (ed.), Borrelia: molecular biology, host interaction and pathogenesis. Calister Academic Press, Norfolk, United Kingdom.

3. Antigenic variation by Borrelia hermsii occurs through recombination between extragenic repetitive elements on linear plasmids

4. Juxtaposition of expressed variable antigen genes with a conserved telomere in the bacterium Borrelia hermsii.

5. Multiple and Diverse vsp and vlp Sequences in Borrelia miyamotoi, a Hard Tick-Borne Zoonotic Pathogen

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