Genome Sequence of Escherichia coli O157:H7 Strain 2886-75, Associated with the First Reported Case of Human Infection in the United States

Author:

Sanjar Fatemeh1,Hazen Tracy H.2,Shah Sadiq M.1,Koenig Sara S. K.1,Agrawal Sonia2,Daugherty Sean2,Sadzewicz Lisa2,Tallon Luke J.2,Mammel Mark K.3,Feng Peter3,Soderlund Robert4,Tarr Phillip I.5,DebRoy Chitrita6,Dudley Edward G.7,Cebula Thomas A.8,Ravel Jacques2,Fraser Claire M.2,Rasko David A.2,Eppinger Mark1

Affiliation:

1. University of Texas at San Antonio, Department of Biology and South Texas Center for Emerging Infectious Diseases, San Antonio, Texas, USA

2. Institute for Genome Sciences (IGS), University of Maryland, School of Medicine, Department of Microbiology and Immunology, Baltimore, Maryland, USA

3. Centers for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, Laurel, Maryland, USA

4. National Veterinary Institute, Department of Bacteriology, SVA, Uppsala, Sweden

5. Washington University School of Medicine, St. Louis, Missouri, USA

6. Pennsylvania State University, Department of Veterinary and Biomedical Sciences, University Park, Pennsylvania, USA

7. Pennsylvania State University, Department of Food Science, University Park, Pennsylvania, USA

8. Johns Hopkins University, Department of Biology, Baltimore, Maryland, USA

Abstract

ABSTRACT First identified in 1982 as a human pathogen, enterohemorrhagic Escherichia coli of the O157:H7 serotype is a major cause of food-borne acquired human infections. Here, we report the genome sequence of the first known strain of this serotype isolated in the United States.

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

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