A Novel Bunyavirus-Like Virus of Trypanosomatid Protist Parasites

Author:

Akopyants Natalia S.1,Lye Lon-Fye1,Dobson Deborah E.1,Lukeš Julius23,Beverley Stephen M.1ORCID

Affiliation:

1. Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA

2. Institute of Parasitology, Biology Centre, and Faculty of Sciences, University of South Bohemia, Ĉeské Budějovice, Czech Republic

3. Canadian Institute for Advanced Research, Toronto, Ontario, Canada

Abstract

ABSTRACT We report here the sequences for all three segments of a novel RNA virus (LepmorLBV1) from the insect trypanosomatid parasite Leptomonas moramango . This virus belongs to a newly discovered group of bunyavirus-like elements termed Leishbunyaviruses (LBV), the first discovered from protists related to arboviruses infecting humans.

Funder

HHS | NIH | National Cancer Institute

HHS | National Institutes of Health

HHS | NIH | National Center for Research Resources

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

Reference9 articles.

1. Plyusnin A, Beaty BJ, Elliott RM, Goldbach R, Kormelink R, Lundkvist KA, Schmaljohn CS, Tesh RB. 2012. Family Bunyaviridae, p 725–741. In King AMQ, Adams MJ, Carstens EB, Lefkowitz EJ (ed), Virus taxonomy: classification and nomenclature of viruses: ninth report of the International Committee on Taxonomy of Viruses. Elsevier Academic, San Diego, CA.

2. Ultrastructure and molecular phylogeny of four new species of monoxenous trypanosomatids from flies (Diptera: Brachycera) with redefinition of the genus Wallaceina

3. Differential Induction of TLR3-Dependent Innate Immune Signaling by Closely Related Parasite Species

4. Bunyavirus: Structure and Replication

5. Recent advances in the molecular and cellular biology of bunyaviruses

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