High-Quality Draft Genome Sequence of Francisella tularensis subsp. holarctica Strain OR96-0246

Author:

Atkins L. M.12,Holder M. E.12,Ajami N. J.12,Metcalf G. A.3,Weissenberger G. M.3,Wang M.3,Vee V.3,Han Y.3,Muzny D. M.3,Gibbs R. A.3,Petrosino J. F.12

Affiliation:

1. Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA

2. Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA

3. Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA

Abstract

ABSTRACT The bacterial pathogen Francisella tularensis was recently renewed as a tier-one select agent. F. tularensis subsp. tularensis (type A) and holarctica (type B) are of clinical relevance. Here, we report the complete genome of a virulent F. tularensis type B strain and describe its usefulness in comparative genomics.

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

Reference13 articles.

1. TULAREMIA

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3. Centers for Disease Control and Prevention. HHS and USDA select agents and toxins: 7CFR part 331 9 CFR part 121 and 42 CFR part 73. Centers for Disease Control and Prevention Atlanta GA. http://www.selectagents.gov/SelectAgentsandToxinsList.html.

4. The Economic Impact of a Bioterrorist Attack: Are Prevention and Postattack Intervention Programs Justifiable?

5. Immunization against Tularemia: Analysis of the Effectiveness of Live Francisella tularensis Vaccine in Prevention of Laboratory-Acquired Tularemia

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