Whole-Genome Sequence of Phage-Resistant Strain Escherichia coli DH5α

Author:

Chen Jingchao1,Li Yi1,Zhang Kun1,Wang Hailei12

Affiliation:

1. Singapore-China Joint Engineering Laboratory for Bioconversion Technology of Functional Microbes, College of Life Sciences, Henan Normal University, Xinxiang, China

2. Advanced Environmental Biotechnology Center, Nanyang Environment and Water Research Institute, Nanyang Technological University, Singapore, Singapore

Abstract

ABSTRACT The genomes of many strains of Escherichia coli have been sequenced, as this organism is a classic model bacterium. Here, we report the genome sequence of Escherichia coli DH5α, which is resistant to a T4 bacteriophage (CCTCC AB 2015375), while its other homologous E. coli strains, such as E. coli BL21, DH10B, and MG1655, are not resistant to phage invasions. Thus, understanding of the genome of the DH5α strain, along with comparative analysis of its genome sequence along with other sequences of E. coli strains, may help to reveal the bacteriophage resistance mechanism of E. coli .

Funder

National Science Foundation of China

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

Reference9 articles.

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