Genome Sequence of Fusobacterium nucleatum Strain W1481, a Possible New Subspecies Isolated from a Periodontal Pocket

Author:

Ang Mia Yang12,Dymock David3,Tan Joon Liang1,Thong Ming Hang1,Tan Qin Kai1,Wong Guat Jah12,Paterson Ian C.24,Choo Siew Woh12

Affiliation:

1. Genome Informatics Research Laboratory, University of Malaya, Kuala Lumpur, Malaysia

2. Department of Oral Biology and Biomedical Sciences, University of Malaya, Kuala Lumpur, Malaysia

3. School of Oral and Dental Sciences, University of Bristol, Bristol, United Kingdom

4. Oral Cancer Research and Coordinating Centre, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia

Abstract

ABSTRACT Fusobacterium nucleatum is a bacterial species commonly detected in dental plaque within the human oral cavity, with some strains associated with periodontal disease, one of the most common clinical bacterial infections in the human body. The exact mechanisms of its pathogenesis are still not completely understood. In this study, we present the genome sequence and annotation of F. nucleatum strain W1481, isolated from a periodontal pocket of a dental patient at the University of Bristol, United Kingdom, the 16S rRNA gene sequencing of which showed it to be markedly different from the five previously named subspecies.

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

Reference21 articles.

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