Divergent Picobirnaviruses in Human Feces-Reference-Cited by-同舟云学术

Divergent Picobirnaviruses in Human Feces

Published:2014-06-26 Issue:3 Volume:2 Page:
ISSN:2169-8287
Container-title:Genome Announcements
language:en
Short-container-title:Genome Announc

Author:

Ng Terry Fei Fan¹²,Vega Everardo³,Kondov Nikola O.¹,Markey Christopher¹,Deng Xutao¹²,Gregoricus Nicole³,Vinjé Jan³,Delwart Eric¹²

Affiliation:

1. Blood Systems Research Institute, San Francisco, California, USA

2. Department of Laboratory Medicine, University of California at San Francisco, San Francisco, California, USA

3. National Calicivirus Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Abstract

ABSTRACT The near-complete genomes of two picobirnaviruses (PBVs) in diarrheal stool samples, human picobirnaviruses D and E (HuPBV-D and -E), were genetically characterized. Their RNA-dependent RNA polymerase (RdRp) protein sequences had <66% identities to known PBVs. Due to a single nucleotide insertion, the open reading frame 2 (ORF2) in segment 1 of HuPBV-D was interrupted by a stop codon. A small stem-loop structure overlying the stop codon may result in translational readthrough into the rest of ORF2.

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/genomeA.00415-14

Reference13 articles.

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