Imaging Clostridioides difficile Spore Germination and Germination Proteins

Author:

Baloh Marko1,Nerber Hailee N.1,Sorg Joseph A.1ORCID

Affiliation:

1. Department of Biology, Texas A&M University, College Station, Texas, USA

Abstract

Germination by C. difficile spores is the first step in the establishment of potentially life-threatening C. difficile infection (CDI). A deeper understanding of the mechanism by which spores germinate may provide insight for how to either prevent spore germination into a disease-causing vegetative form or trigger germination prematurely when the spore is either in the outside environment or in a host environment that does not support the establishment of colonization/disease.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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