Meropenem Population Pharmacokinetics and Simulations in Plasma, Cerebrospinal Fluid, and Brain Tissue-Reference-Cited by-同舟云学术

Meropenem Population Pharmacokinetics and Simulations in Plasma, Cerebrospinal Fluid, and Brain Tissue

Published:2022-08-16 Issue:8 Volume:66 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Alshaer Mohammad H.¹²^ORCID,Barlow Brooke³,Maranchick Nicole¹²,Moser Miriam⁴,Gramss Leon⁴,Burgmann Heinz⁵,Jalali Valentin Al⁶,Wölfl-Duchek Michael⁶,Jäger Walter⁷,Poschner Stefan⁷,Plöchl Walter⁸,Reinprecht Andrea⁴,Rössler Karl⁴,Gruber Andreas⁹,Zeitlinger Markus⁶^ORCID,Peloquin Charles A.¹²^ORCID,Hosmann Arthur⁴

Affiliation:

1. Infectious Disease Pharmacokinetics Lab, Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA

2. Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, Florida, USA

3. Department of Pharmacy, UF Health Shands Hospital, Gainesville, Florida, USA

4. Department of Neurosurgery, Medical University of Vienna, Vienna, Austria

5. Department of Internal Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria

6. Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria

7. Department of Pharmaceutical Sciences, University of Vienna, Vienna, Austria

8. Department of Anesthesia, General Intensive Care Medicine and Pain Management, Medical University of Vienna, Vienna, Austria

9. Department of Neurosurgery, Johannes Kepler University, Linz, Austria

Abstract

Meropenem is a broad spectrum carbapenem used for the treatment of cerebral infections. There is a need for data describing meropenem pharmacokinetics (PK) in the brain tissue to optimize therapy in these infections.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/aac.00438-22

Reference22 articles.

1. Clinical Characteristics and Predictors of Adverse Outcome in Adult and Pediatric Patients With Healthcare-Associated Ventriculitis and Meningitis

2. Nosocomial Bacterial Meningitis

3. A meta-analysis of ventriculostomy-associated cerebrospinal fluid infections

4. 2017 Infectious Diseases Society of America’s Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis*

5. Cerebrospinal fluid penetration of meropenem in neurocritical care patients with proven or suspected ventriculitis: a prospective observational study

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