Characterization of chromosomal DNA profiles from Helicobacter pylori strains isolated from sequential gastric biopsy specimens

Author:

Salama S M1,Jiang Q1,Chang N1,Sherbaniuk R W1,Taylor D E1

Affiliation:

1. Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Canada.

Abstract

The restriction endonuclease profiles of DNAs from Helicobacter pylori strains isolated from 20 patients in two or more consecutive biopsy specimens over a period of up to 2 years were analyzed by pulsed-field gel electrophoresis with NotI and NruI. H. pylori strains possess a high degree of genomic diversity which was not observed to occur in vivo, and attempts to observe it in vitro were not successful.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference17 articles.

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