Practical Comparison of the BioFire FilmArray Pneumonia Panel to Routine Diagnostic Methods and Potential Impact on Antimicrobial Stewardship in Adult Hospitalized Patients with Lower Respiratory Tract Infections-Reference-Cited by-同舟云学术

Practical Comparison of the BioFire FilmArray Pneumonia Panel to Routine Diagnostic Methods and Potential Impact on Antimicrobial Stewardship in Adult Hospitalized Patients with Lower Respiratory Tract Infections

Published:2020-06-24 Issue:7 Volume:58 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Buchan Blake W.¹^ORCID,Windham Sam¹,Balada-Llasat Joan-Miquel²,Leber Amy³,Harrington Amanda⁴,Relich Ryan⁵,Murphy Caitlin⁶,Dien Bard Jennifer⁷,Naccache Samia⁷,Ronen Shira¹,Hopp Amanda¹,Mahmutoglu Derya¹,Faron Matthew L.¹,Ledeboer Nathan A.¹,Carroll Amanda²,Stone Hannah²,Akerele Oluseun²,Everhart Kathy³,Bonwit Andrew⁴,Kwong Christina⁴,Buckner Rebecca⁵,Warren Del⁵,Fowler Randal⁶,Chandrasekaran Sukantha⁸,Huse Holly⁸,Campeau Shelley⁸,Humphries Romney⁸,Graue Corrin⁹,Huang Angela¹¹⁰

Affiliation:

1. The Medical College of Wisconsin, Milwaukee, Wisconsin, USA

2. The Ohio State University, Columbus, Ohio, USA

3. Nationwide Children’s Hospital, Columbus, Ohio, USA

4. Loyola University Medical Center, Maywood, Illinois, USA

5. Indiana University School of Medicine, Indianapolis, Indiana, USA

6. University of Nebraska Medical Center, Omaha, Nebraska, USA

7. Children’s Hospital of Los Angeles, Los Angeles, California, USA

8. University of California Los Angeles, Los Angeles, California, USA

9. BioFire Diagnostics, LLC, Salt Lake City, Utah, USA

10. Froedtert Hospital, Milwaukee, Wisconsin, USA

Abstract

Lower respiratory tract infections, including hospital-acquired and ventilator-associated pneumonia, are common in hospitalized patient populations. Standard methods frequently fail to identify the infectious etiology due to the polymicrobial nature of respiratory specimens and the necessity of ordering specific tests to identify viral agents. The potential severity of these infections combined with a failure to clearly identify the causative pathogen results in administration of empirical antibiotic agents based on clinical presentation and other risk factors.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00135-20

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