Affiliation:
1. Faculty of Pharmaceutical Sciences, The University of Tokushima, Tokushima 770-8505, Japan
Abstract
ABSTRACT
We have demonstrated that 6,7-dihydroxyflavone by itself has only a weak antibacterial effect on methicillin-resistant
Staphylococcus aureus
(MRSA) but that at concentrations less than MIC it synergistically elevates the susceptibility of clinically isolated MRSA and methicillin-sensitive
S. aureus
strains to β-lactam antibiotics from 8- to 32,800-fold.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
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