Author:
Charon N W,Johnson R C,Muschel L H
Abstract
Normal serum from the painted turtle (Chrysemys picta), the snapping turtle (Chelydra serpentina), and the frog (Rana pipiens) were found to possess bactericidal activity towards Leptospira. Leptospires from both the parasitic and biflexa complexes were killed by these sera at high dilutions. This pattern differs from that of mammalian serum, as generally only the biflexa complex leptospires are killed by normal mammalian serum. The activity in C. picta serum was characterized as being complement dependent and not mediated by basic proteins. Because comple-inactivated C. picta serum regained leptospiricidal activity after the addition of fresh rabbit serum, antibody is also likely to participate in the killing activity. Further support that C. picta serum contained leptospiral antibodies was found by the detection of serotype-specific agglutinins.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference27 articles.
1. Experimental infections with Leptospira pomona in snakes and turtles;Abdulla P. K.;Zoonoses Res.,1962
2. Leptospiral agglutinins in sera from southern Illinois herpetofauna;Andrews R. D.;Bull. Wild. Dis. Assoc.,1965
3. Systematics of a Leptospira strain isolated from frog;Babudieri B.;Experentia,1972
4. Buchanan R. E. and N. E. Gibbons (ed.). 1974. Bergey's manual of determinative bacteriology 8th ed. The Williams & Wilkins Company Baltimore.
5. Quantitative studies on spheroplast formation by the complement system and Iysozyme on gram negative bacteria;Crombie L. B.;Proc. Soc. Exp. Biol. Med.,1967
Cited by
13 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献