Genetic, Functional, and Immunogenic Analyses of the <i>O</i> -Linked Protein Glycosylation System in Neisseria meningitidis Serogroup A ST-7 Isolates-Reference-Cited by-同舟云学术

Genetic, Functional, and Immunogenic Analyses of the O -Linked Protein Glycosylation System in Neisseria meningitidis Serogroup A ST-7 Isolates

Published:2023-03-21 Issue:3 Volume:205 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Næss Lisbeth M.¹,Maugesten Ingunn S.¹,Caugant Dominique A.¹²,Kassu Afework³,Aseffa Abraham³,Børud Bente¹

Affiliation:

1. Division of Infection Control, Norwegian Institute of Public Health, Oslo, Norway

2. Department of Community Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway

3. Armauer Hansen Research Institute, Addis Ababa, Ethiopia

Abstract

Bacterial meningitis is a serious global health problem, and one of the major causative organisms is Neisseria meningitidis . Extensive variability in protein glycan structure and antigenicity is due to phase variation of protein glycosylation genes and polymorphic gene content and function.

Funder

Renee og Bredo Grimsgaard's Foundation

Research Council of Norway

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.00458-22

Reference61 articles.

1. Neisseria meningitidis: Biology, Microbiology, and Epidemiology

2. Meningococcal carriage by age: a systematic review and meta-analysis