Cefuroxime axetil for treatment of uncomplicated gonorrhea

Author:

Gottlieb A,Mills J

Abstract

Oral cefuroxime axetil (1 g) plus probenecid cured 29 of 30 urethral and 6 of 6 rectal gonococcal infections in men; alone the drug cured 22 of 23 urethral and 4 of 6 rectal infections. No toxicity was observed. Cefuroxime axetil alone is effective for urethral gonorrhea in males; rectal gonorrhea probably requires additional probenecid.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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3. Treatment efficacy for rectal Neisseria gonorrhoeae: a systematic review and meta-analysis of randomized controlled trials;Journal of Antimicrobial Chemotherapy;2021-08-30

4. Cefuroxime;Kucers' The Use of Antibiotics Sixth Edition;2010-10-29

5. Update on the Management of Gonorrhea in Adults in the United States;Clinical Infectious Diseases;2007-04-01

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