Susceptibility of Campylobacter pyloridis to three macrolide antibiotics (erythromycin, roxithromycin [RU 28965], and CP 62,993) and rifampin-Reference-Cited by-同舟云学术

Susceptibility of Campylobacter pyloridis to three macrolide antibiotics (erythromycin, roxithromycin [RU 28965], and CP 62,993) and rifampin

Published:1986-08 Issue:2 Volume:30 Page:328-329
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Czinn S,Carr H,Aronoff S

Abstract

The presence of Campylobacter pyloridis in the gastric mucosa was recently linked to peptic ulcer disease. This study compared the inhibitory activity of three macrolide compounds (erythromycin, roxithromycin [RU 28965], and CP 62,993) and rifampin against 10 clinical isolates of C. pyloridis. The macrolides were equally effective against the test strains, with MICs ranging from 0.06 to 0.5 microgram/ml; rifampin was less active, with MICs ranging from 0.25 to greater than 1 microgram/ml. Erythromycin and the two new macrolide derivatives are potentially useful agents in the treatment of infections caused by C. pyloridis.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.30.2.328

Reference13 articles.

1. In vitro comparison of the activity of RU 28965, a new macrolide, with that of erythromycin against aerobic and anaerobic bacteria;Barlam T.;Antimicrob. Agents Chemother.,1984

2. In vitro susceptibilities of Campylobacter-like organisms to twenty antimicrobial agents;Flores B. M.;Antimicrob. Agents Chemother.,1985

3. Fricker C. R. and R. W. A. Park. 1985. Urease positive campylobacters. Lancet i:394.

4. Goossens H. P. De Mol H. Coignau J. Levy 0. Grados G. Ghysels H. Innocent and J.-P. Butzler. 1985. Comparative in vitro activities of aztreonam ciprofloxain norfloxacin NOTES 329

5. Campylobacter-like organisms on the gastric mucosa: culture, histological and serological studies;Jones D. M.;J. Clin. Pathol.,1984

Cited by 30 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Helicobacter pylori Infection;Pediatric Gastroenterology;2008

2. Helicobacter pylori infection in children;Current Problems in Pediatrics;2001-09

3. Antimicrobial susceptibility testing of 230 Helicobacter pylori strains: importance of medium, inoculum, and incubation time;Antimicrobial Agents and Chemotherapy;1997-12

4. Cure of Helicobacter pylori infection in the elderly: effects of eradication on gastritis and serological markers;Alimentary Pharmacology & Therapeutics;1996-10

5. Prospective evaluation of the macrolide antibiotic dirithromycin for the treatment of Helicobacter pylori.;Alimentary Pharmacology & Therapeutics;1996-06