Abstract
Ammonium chloride added to normal resident mouse peritoneal macrophages reduced the rate of killing of ingested Saccharomyces cerevisiae. It is suggested that this is attributable to the inhibition by ammonia of phagosome-lysosome fusion or of lysosomal protein degradation and that, consequently, lysosomal mechanisms contribute to the normal killing of these yeasts.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
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