Poor Diagnostic Accuracy of Commercial Antibody-Based Assays for the Diagnosis of Acute Chikungunya Infection-Reference-Cited by-同舟云学术

Poor Diagnostic Accuracy of Commercial Antibody-Based Assays for the Diagnosis of Acute Chikungunya Infection

Published:2011-10 Issue:10 Volume:18 Page:1773-1775
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Blacksell Stuart D.¹²,Tanganuchitcharnchai Ampai¹,Jarman Richard G.³,Gibbons Robert V.³,Paris Daniel H.¹²,Bailey Mark S.⁴,Day Nicholas P. J.¹²,Premaratna Ranjan⁵,Lalloo David G.⁶,de Silva H. Janaka⁵

Affiliation:

1. Mahidol University—Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Bangkok 10400, Thailand

2. Centre for Tropical Medicine, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, England

3. Armed Forces Research Institute of Medical Sciences, 315/6 Rajvithi Road, Bangkok 10400, Thailand

4. Department of Military Medicine, Royal Centre for Defence Medicine, Vincent Drive, Birmingham B15 2SQ, England

5. Department of Medicine, University of Kelaniya, P.O. Box 6, Thalagolla Road, Ragama, Sri Lanka

6. Clinical Research Group, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, England

Abstract

ABSTRACT A Sri Lankan fever cohort ( n = 292 patients; 17.8% prevalence) was used to assess two standard diagnostic Chikungunya IgM tests. The immunochromatographic test (ICT) acute sample sensitivity (SN) was 1.9 to 3.9%, and specificity (SP) was 92.5 to 95.0%. The enzyme-linked immunosorbent assay (ELISA) gave an acute sample SN of 3.9% and an SP of 92.5% and a convalescent sample SN of 84% and an SP of 91%. These assays are not suitable for the acute diagnosis of Chikungunya virus infection.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CVI.05288-11

Reference13 articles.

1. The Comparative Accuracy of 8 Commercial Rapid Immunochromatographic Assays for the Diagnosis of Acute Dengue Virus Infection

2. Techniques for Hemagglutination and Hemagglutination-Inhibition with Arthropod-Borne Viruses

3. Estimating Chikungunya prevalence in La Réunion Island outbreak by serosurveys: Two methods for two critical times of the epidemic

4. Concurrent outbreaks of Chikungunya and Dengue fever in Kandy, Sri Lanka, 2006-07: a comparative analysis of clinical and laboratory features

5. Rapid and real-time detection technologies for emerging viruses of biomedical importance

Cited by 43 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Systemic and Ophthalmic Manifestations of Chikungunya Fever;Ocular Immunology and Inflammation;2023-09-29

2. Evaluating the Performance of the DPP® ZDC IgM/IgG Rapid Test for Chikungunya Virus Diagnosis in Febrile Outpatients: A Prospective, Diagnostic Accuracy Study;2023-05-01

3. Diagnostic accuracy of serological tests for the diagnosis of Chikungunya virus infection: A systematic review and meta-analysis;PLOS Neglected Tropical Diseases;2022-02-04

4. A Rare Case of Severe Neutropenia Due to Chikungunya Fever Which Improved With Filgrastim;Cureus;2021-12-28

5. Current state of chikungunya fever laboratory diagnosis (review of literature);Russian Clinical Laboratory Diagnostics;2021-09-10