EXTRACTION AND PRELIMINARY CHARACTERIZATION OF A HEPATOTOXIC SUBSTANCE FROM CULTURES OF PENICILLIUM RUBRUM-Reference-Cited by-同舟云学术

EXTRACTION AND PRELIMINARY CHARACTERIZATION OF A HEPATOTOXIC SUBSTANCE FROM CULTURES OF PENICILLIUM RUBRUM

Published:1962-08 Issue:2 Volume:84 Page:283-290
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Wilson Benjamin J.¹,Wilson Christina H.¹

Affiliation:

1. Microbiological Research Laboratory, David Lipscomb College, Nashville, Tennessee

Abstract

Wilson, Benjamin J. (David Lipscomb College, Nashville, Tenn.) and Christina H. Wilson . Extraction and preliminary characterization of a hepatotoxic substance from cultures of Penicillium rubrum . J. Bacteriol. 84: 283–290. 1962.—A toxic acidic substance was extracted from cultures of Penicillium rubrum P-13 grown on corn-sucrose medium. Administration to mice, guinea pigs, rabbits, and dogs produced hepatotoxic and hemorrhagic syndromes. These findings were similar to those previously reported in which livestock were fed feedstuff infected with pure cultures of the fungus. Preliminary studies were made of the physical and chemical properties of the toxic material.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.84.2.283-290.1962

Reference11 articles.

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