In Vitro Killing of Nosocomial Pathogens by Acid and Acidified Nitrite-Reference-Cited by-同舟云学术

In Vitro Killing of Nosocomial Pathogens by Acid and Acidified Nitrite

Published:2006-11 Issue:11 Volume:50 Page:3901-3904
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Rao Agam¹,Jump Robin L. P.¹,Pultz Nicole J.²,Pultz Michael J.²,Donskey Curtis J.²

Affiliation:

1. Department of Medicine, University Hospitals of Cleveland, Cleveland, Ohio

2. Research Service, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio

Abstract

ABSTRACT Exposure to pH 1 or 2 buffers or acidic gastric contents resulted in the killing of vancomycin-resistant Enterococcus sp., Klebsiella pneumoniae , Staphylococcus aureus , and Candida glabrata but not Clostridium difficile spores. Nitrite enhanced killing under acidic conditions, but significant killing of C. difficile spores required nitrite concentrations above usual physiological levels.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01506-05

Reference18 articles.

1. Ben-Ami, R., M. J. Schwaber, S. Navon-Venezia, D. Schwartz, M. Giladi, I. Chmelnitsky, A. Leavitt, and Y. Carmeli. 2006. Influx of extended-spectrum β-lactamase-producing enterobacteriaceae into the hospital. Clin. Infect. Dis.42:925-934.

2. Dial, S., K. Alrasadi, C. Manoukian, A. Huang, and D. Menzies. 2004. Risk of Clostridium difficile diarrhea among hospital inpatients prescribed proton pump inhibitors: cohort and case-control studies. CMAJ171:33-38.

3. Dial, S., J. A. Delaney, A. N. Barkun, and S. Suissa. 2005. Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease. JAMA294:2989-2995.

4. Donskey, C. J., J. R. Schreiber, M. R. Jacobs, R. Shekar, R. A. Salata, S. Gordon, C. C. Whalen, F. Smith, and L. B. Rice. 1999. A polyclonal outbreak of predominantly vanB vancomycin-resistant enterococci in northeast Ohio. Clin. Infect. Dis.29:573-579.

5. Donskey, C. J. 2004. The role of the intestinal tract as a reservoir and source for transmission of nosocomial pathogens. Clin. Infect. Dis.39:219-226.

Cited by 57 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Gut Microbiota Composition Associated with Clostridioides difficile Colonization and Infection;Pathogens;2022-07-08

2. Ischemic Colitis Is a Risk Factor for Clostridium difficile Infection;Cureus;2022-06-19

3. Achieving Partial Nitritation by Treating Sludge With Free Nitrous Acid: The Potential Role of Quorum Sensing;Frontiers in Microbiology;2022-04-27

4. Heme oxygenase-1, carbon monoxide, and malaria – The interplay of chemistry and biology;Coordination Chemistry Reviews;2022-02

5. Prevention of Infection due to Clostridium (Clostridioides) difficile;Infectious Disease Clinics of North America;2021-12