A Systematic Evaluation of IgM and IgG Antibody Assay Accuracy in Diagnosing Acute Zika Virus Infection in Brazil: Lessons Relevant to Emerging Infections-Reference-Cited by-同舟云学术

A Systematic Evaluation of IgM and IgG Antibody Assay Accuracy in Diagnosing Acute Zika Virus Infection in Brazil: Lessons Relevant to Emerging Infections

Published:2021-11-18 Issue:12 Volume:59 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Medialdea-Carrera Raquel¹^ORCID,Levy Flavia²,Castanha Priscila³⁴^ORCID,Carvalho de Sequeira Patricia²,Brasil Patricia⁵,Lewis-Ximenez Lia L.⁶,Turtle Lance¹⁷,Solomon Tom¹⁸,Bispo de Filippis Ana Maria²,Brown David W.²⁹,Griffiths Michael J.¹¹⁰^ORCID

Affiliation:

1. National Institute for Health Research (NIHR) Health Protection Research Unit in Emerging and Zoonotic Infections (HPRU EZI), Institute of Infection and Global Health, University of Liverpool, Liverpool, UK

2. Flavivirus Reference Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil

3. Aggeu Magalhães Research Center, Oswaldo Cruz Foundation (FIOCRUZ), Recife, Pernambuco, Brazil

4. Faculty of Medical Science/Institute of Biological Science, University of Pernambuco, Recife, Pernambuco, Brazil

5. Evandro Chagas National Institute of Infectious Diseases; Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil

6. Viral Hepatitis Clinic, Viral Hepatitis National Reference Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil

7. Tropical & Infectious Disease Unit, Royal Liverpool University Hospital (member of Liverpool Health Partners), Liverpool, UK

8. The Walton Centre NHS Foundation Trust, Liverpool, UK

9. Public Health England, London, UK

10. Alder Hey Children's NHS Foundation Trust, Liverpool, UK

Abstract

Accurate diagnostics underpin effective public health responses to emerging viruses. For viruses, such as Zika virus (ZIKV), where the viremia clears quickly, antibody-based (IgM or IgG) diagnostics are recommended for patients who present 7 days after symptom onset.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.02893-20

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