Human Cytomegalovirus Resistance to Antiviral Drugs-Reference-Cited by-同舟云学术

Human Cytomegalovirus Resistance to Antiviral Drugs

Published:2005-03 Issue:3 Volume:49 Page:873-883
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Gilbert C.¹,Boivin G.¹

Affiliation:

1. Research Center in Infectious Diseases of the Centre Hospitalier Universitaire de Québec, and Department of Medical Biology, Université Laval, Sainte-Foy, Québec, Canada

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.49.3.873-883.2005

Reference139 articles.

1. Baldanti, F., D. Lilleri, G. Campanini, G. Comolli, A. L. Ridolfo, S. Rusconi, and G. Gerna. 2004. Human cytomegalovirus double resistance in a donor-positive/recipient-negative lung transplant patient with an impaired CD4-mediated specific immune response. J. Antimicrob. Chemother.53:536-539.

2. Baldanti, F., D. Michel, L. Simoncini, M. Heuschmid, A. Zimmermann, R. Minisini, P. Schaarschmidt, T. Schmid, G. Gerna, and T. Mertens. 2002. Mutations in the UL97 ORF of ganciclovir-resistant clinical cytomegalovirus isolates differentially affect GCV phosphorylation as determined in a recombinant vaccinia virus system. Antivir. Res.54:59-67.

3. Baldanti, F., S. Paolucci, A. Parisi, L. Meroni, and G. Gerna. 2002. Emergence of multiple drug-resistant human cytomegalovirus variants in 2 patients with human immunodeficiency virus infection unresponsive to highly active antiretroviral therapy. Clin. Infect. Dis.34:1146-1149.

4. A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate

5. Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recovered from patients with AIDS

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