Antimicrobial Susceptibilities of Helicobacter pylori Isolates under Microaerophilic Atmospheres Established by Two Different Methods

Author:

Kobayashi Intetsu1,Muraoka Hiroe1,Saika Takeshi1,Nishida Minoru1,Fujioka Toshio2,Nasu Masaru2

Affiliation:

1. Chemotherapy Division, Mitsubishi Kagaku Bio-Clinical Laboratories, Inc., Tokyo,1 and

2. Second Department of Internal Medicine, Oita Medical University, Oita,2 Japan

Abstract

ABSTRACT The MICs of clarithromycin, amoxicillin, and metronidazole for 150 Helicobacter pylori isolates were determined using the AnaeroPack system and were compared with those determined using a microaerophilic incubator. The MICs of clarithromycin, amoxicillin, and metronidazole determined under both microaerophilic atmospheres were mostly within one twofold dilution for 146 (97.3%), 150 (100%), and 149 (99.3%) of the isolates, respectively.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference13 articles.

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3. Grasmick A. Processing and interpretation of bacterial fecal cultures Clinical microbiology procedures handbook. Isenberg H. D. 1994 1.10.1 1.10.25 American Society for Microbiology Washington D.C.

4. Eradication of Helicobacter pylori using one-week triple therapies combining omeprazole with two antimicrobials: the MACH1 study;Lind T.;Helicobacter,1996

5. Effect of pH variation on the susceptibility of Helicobacter pylori to three macrolide antimicrobial agents and temafloxacin;Malanoski G. J.;Eur. J. Clin. Microbiol. Infect. Dis.,1993

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