Limited Level of Accuracy Provided by Available Rapid Diagnosis Tests for Malaria Enhances the Need for PCR-Based Reference Laboratories

Author:

Rubio J. M.1,Buhigas I.2,Subirats M.2,Baquero M.2,Puente S.3,Benito A.1

Affiliation:

1. Department of Parasitology, National Center for Microbiology,1 Carlos III National Institute of Health, Madrid, Spain

2. Department of Microbiology2 and

3. Department of Infectious Diseases,3 Carlos III Hospital, and

Abstract

ABSTRACT The rise of imported malaria cases and the high fatality rate in Europe make the search for new and easy diagnostic methods necessary. Rapid diagnosis tests (RDTs) are, in part, developed to cover the lack of diagnosis experience. Unfortunately, our data suggest that the accuracy of RDTs is insufficient and could increase the number of incorrect malaria diagnoses.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference5 articles.

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2. Imported malaria: prospective analysis of problems in diagnosis and management;Kain K. C.;Clin. Infect. Dis.,1998

3. Malaria surveillance in Italy: 1997 analysis and 1998 provisional data;Romi R.;Eurosurveillance,1999

4. Usefulness of Seminested Multiplex PCR in Surveillance of Imported Malaria in Spain

5. World Health Organization New perspectives: malaria diagnosis. Report of a joint WHO/USAID informal consultation 25-7 October. 1999 World Health Organization Geneva Switzerland

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