Clinical Isolates of Staphylococcus intermedius Masquerading as Methicillin-Resistant Staphylococcus aureus

Author:

Pottumarthy Sudha1,Schapiro Jeffrey M.1,Prentice Jennifer L.1,Houze Yolanda B.1,Swanzy Susan R.1,Fang Ferric C.12,Cookson Brad T.12

Affiliation:

1. Departments of Laboratory Medicine

2. Microbiology, University of Washington, Seattle, Washington

Abstract

ABSTRACT Staphylococcus intermedius is a zoonotic organism that can be associated with human disease. We report two separate cases of S. intermedius infection in which a false-positive rapid penicillin binding protein 2a latex test in conjunction with the phenotypic properties of β-hemolysis and coagulase positivity allowed the clinical isolates to masquerade as methicillin-resistant Staphylococcus aureus . 16S rRNA gene sequencing and the absence of mecA revealed the strains to be methicillin-susceptible S. intermedius .

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference22 articles.

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2. Development of Methicillin Resistance in Clinical Isolates of Staphylococcus sciuri by Transcriptional Activation of the mecA Homologue Native to the Species

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4. Gortel, K., K. L. Campbell, I. Kakoma, T. Whittem, D. J. Schaeffer, and R. M. Weisiger. 1999. Methicillin resistance among staphylococci isolated from dogs. Am. J. Vet. Res.60:1526-1530.

5. Detection of Methicillin-Resistant Staphylococcus aureus and Simultaneous Confirmation by Automated Nucleic Acid Extraction and Real-Time PCR

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