Fatal Cerebral Phaeohyphomycosis Due to Curvularia lunata in an Immunocompetent Patient

Author:

Carter Elliot1,Boudreaux Carole1

Affiliation:

1. Department of Pathology, University of South Alabama, Mobile, Alabama

Abstract

ABSTRACT Curvularia infections in humans are relatively uncommon despite the ubiquitous presence of this soil-dwelling dematiaceous fungus in the environment. Originally thought to be solely a pathogen of plants, Curvularia has been described as a pathogen of humans and animals in the last half-century, causing respiratory tract, cutaneous, and corneal infections. Only three previous cases of central nervous system involvement by Curvularia have been documented in the medical literature. We report a fatal case of cerebral Curvularia infection in which there was no known history of immunocompromise or prior respiratory tract or sinus infection in the patient.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference18 articles.

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3. Berry, A. J., T. M. Kerkering, A. M. Giordano, and J. Chiancone. 1984. Phaeohyphomycotic sinusitis. Pediatr. Infect. Dis. J.3:150-152.

4. de la Monte, S. M., and G. M. Hutchins. 1985. Disseminated Curvularia infection. Arch. Pathol. Lab. Med.109:872-874.

5. Ebright, J. R., P. H. Chandrasekar, S. Marks, M. R. Fairfax, A. Aneziokoro, and M. R. McGinnis. 1999. Invasive sinusitis and cerebritis due to Curvularia clavata in an immunocompetent adult. Clin. Infect. Dis.28:687-689.

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