Usefulness of PCR Analysis for Diagnosis of Alveolar Echinococcosis with Unusual Localizations: Two Case Studies

Author:

Georges Sophie1,Villard Odile1,Filisetti Denis1,Mathis Alexander2,Marcellin Luc3,Hansmann Yves4,Candolfi Ermanno1

Affiliation:

1. Institut de Parasitologie et Pathologie Tropicale, Faculté de Médecine

2. Institut für Parasitologie, Universität Zürich, Zurich, Switzerland

3. Service d'Anatomie Pathologique Générale

4. Service de Maladies Infectieuses et Tropicales, Hôpitaux Universitaires de Strasbourg, Strasbourg, France

Abstract

ABSTRACT The report presents two cases where diagnosis of alveolar echinococcosis was confirmed by Echinococcus multilocularis and Echinococcus granulosus PCR. The extrahepatic osseous involvement and the absence of initial hepatic involvement are unusual in both cases. Due to limitations of serological interpretation, PCR was useful to diagnose atypical echinococcosis.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference22 articles.

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2. Chiboub, H., F. Boutayeb, S. Wahbi, M. El Yacoubi, N. Ouazzani, and M. Hermas. 2001. Echinococcosis of the pelvic bone: four cases. Rev. Chir. Orthop. Reparatrice Appar. Mot.87:397-401.

3. Claudon, M., S. Bracard, F. Plenat, D. Regent, P. Bernadac, and L. Picard. 1987. Spinal involvement in alveolar echinococcosis: assessment of two cases. Radiology162:571-572.

4. Craig, P. 2003. Echinococcus multilocularis. Curr. Opin. Infect. Dis.16:437-444.

5. Diebold-Berger, S., H. Khan, B. Gottstein, E. Puget, J. L. Frossard, and S. Remadi. 1997. Cytologic diagnosis of isolated pancreatic alveolar hydatid disease with immunologic and PCR analyses. A case report. Acta Cytol.41:1381-1386.

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