Molecular Epidemiology of Disease Due to Mycobacterium bovis in Humans in the United Kingdom

Author:

Gibson Andrea L.1,Hewinson Glyn2,Goodchild Tony2,Watt Brian3,Story Alistair4,Inwald Jacqueline2,Drobniewski Francis A.1

Affiliation:

1. Mycobacterium Reference Unit, Health Protection Agency, and Department of Microbiology, Guy's, King's and St Thomas' School of Medicine, King's College Hospital (Dulwich), East Dulwich Grove, London, SE22 8QF

2. Veterinary Laboratory Agency, Weybridge, New Haw, Surrey KT15 3NB

3. Scottish Mycobacteria Reference Laboratory, Royal Infirmary, Little France, Edinburgh EH16 4SA

4. HPA, Communicable Disease Surveillance Centre, Colindale, London NW9 5EQ, United Kingdom

Abstract

ABSTRACT Mycobacterium bovis is the causative agent of bovine tuberculosis, with a wide host range. Fifty human M. bovis isolates were typed using spoligotyping and variable number tandem repeats (VNTR). Fifteen of these spoligotypes have not yet been recorded in cattle. The predominant spoligotype in humans and cattle was subdivided by VNTR.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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