Antigen Assay with the Potential To Aid in Diagnosis of Blastomycosis

Author:

Durkin Michelle1,Witt John1,LeMonte Ann1,Wheat Blair1,Connolly Patricia1

Affiliation:

1. MiraVista Diagnostics/MiraBella Technologies, Indianapolis, Indiana

Abstract

ABSTRACT We report results of an immunoassay for Blastomyces dermatitidis antigenuria. Sensitivity was 92.9%, and specificity was 79.3%. Cross-reactions occurred in 96.3% of patients with histoplasmosis, 100% of patients with paracoccidioidomycosis, 70% of patients with penicilliosis marneffei, 2.9% of patients with cryptococcosis, and 1.1% of patients with aspergillosis. Reproducibility was 96.3%. These findings support a potential role for antigen testing in blastomycosis.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference13 articles.

1. Bland, J. M., and D. G. Altman. 1986. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet1:307-310.

2. Bradsher, R. W., S. W. Chapman, and P. G. Pappas. 2003. Blastomycosis. Infect. Dis. Clin. N. Am.17:21-40, vii.

3. Chapman, S. W., A. C. Lin, K. A. Hendricks, R. L. Nolan, M. M. Currier, K. R. Morris, and H. R. Turner. 1997. Endemic blastomycosis in Mississippi: epidemiological and clinical studies. Semin. Respir. Infect.12:219-228.

4. Comparison of radioimmunoassay and enzyme-linked immunoassay methods for detection of Histoplasma capsulatum var. capsulatum antigen

5. Fisher, M. A., A. M. Legendre, and G. M. Scalarone. 1997. Immunological and chemical characterization of glycoproteins in IEF fractions of Blastomyces dermatitidis yeast lysate antigen. Mycoses40:83-90.

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