Affiliation:
1. Old Dominion University, Department of Chemistry and Biochemistry, Norfolk, Virginia, USA
Abstract
It has recently become evident that the bacterial stringent response is regulated by a triphosphate alarmone (pGpp) as well as the canonical tetra- and pentaphosphate alarmones ppGpp and pppGpp [together, (p)ppGpp]. Often dismissed in the past as an artifact or degradation product, pGpp has been confirmed as a deliberate endpoint of multiple synthetic pathways utilizing GMP, (p)ppGpp, or GDP/GTP as precursors.
Funder
National Science Foundation
U.S. Department of Defense
Virginia Space Grant Consortium
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Cited by
2 articles.
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