Affiliation:
1. Service de Bactériologie-Virologie-Hygiène, Hôpital St-Louis, 75475 Paris Cedex 10,1
2. Collection de l’Institut Pasteur, 75724 Paris Cedex 15,2 and
3. Service de Bactériologie-Virologie, Hôpital Cochin, 75679 Paris Cedex 14,3 France
Abstract
ABSTRACT
Lactobacilli recovered from the blood, cerebrospinal fluid, respiratory tract, and gut of 20 hospitalized immunocompromised septic patients were analyzed. Biochemical carbohydrate fermentation and total soluble cell protein profiles were used to identify the species. Hydrogen peroxide production was measured. Susceptibility to 19 antibiotics was tested by a diffusion method, and the MICs of benzylpenicillin, amoxicillin, imipenem, erythromycin, vancomycin, gentamicin, and levofloxacin were determined. A small number of species produced H
2
O
2
, and antibiotic susceptibilities were species related. Eighteen (90%) of the isolates were
L. rhamnosus
, one was
L. paracasei
subsp.
paracasei
, and one was
L. crispatus
.
L. rhamnosus
,
L. paracasei
subsp.
paracasei
isolates, and the type strains were neither H
2
O
2
producers nor vancomycin susceptible (MICs, ≥256 μg/ml).
L. crispatus
, as well as most of the type strains of lactobacilli which belong to the
L. acidophilus
group, was an H
2
O
2
producer and vancomycin susceptible (MICs, <4 μg/ml).
Publisher
American Society for Microbiology
Cited by
93 articles.
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