The IS 6110 Restriction Fragment Length Polymorphism in Particular Multidrug-Resistant Mycobacterium tuberculosis Strains May Evolve Too Fast for Reliable Use in Outbreak Investigation-Reference-Cited by-同舟云学术

The IS 6110 Restriction Fragment Length Polymorphism in Particular Multidrug-Resistant Mycobacterium tuberculosis Strains May Evolve Too Fast for Reliable Use in Outbreak Investigation

Published:1999-03 Issue:3 Volume:37 Page:788-791
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Alito Alicia¹,Morcillo Nora²,Scipioni Silvia²,Dolmann Alberto²,Romano María I.³,Cataldi Angel³,van Soolingen Dick⁴

Affiliation:

1. Pathobiology Institute CICV/INTA1 and

2. Dr. Cetrángolo Hospital, Vte. López,2Argentina, and

3. Biotechnology Institute CICV/INTA,3 Morón, and

4. National Institute of Public Health and the Environment, 3720 BA Bilthoven, The Netherlands4

Abstract

ABSTRACT To study possible nosocomial transmission of multidrug-resistant (MDR) Mycobacterium tuberculosis , strain types and other information on 24, mostly human immunodeficiency virus-positive patients, were collected. Isolates from 11 patients had identical IS 6110 restriction fragment length polymorphism (RFLP) patterns as well as spoligotype patterns and resistance profiles. Noticeably, nine other isolates from related cases also exhibited identical spoligotypes but slightly different RFLP patterns. These results indicate that for some MDR strains, the evolutionary clock of IS 6110 RFLP may run too fast for reliable interpretation of strain typing results over a period of a few years.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.37.3.788-791.1999

Reference22 articles.

1. Origin and interstate spread of a New York City multidrug-resistant Mycobacterium tuberculosis clone family;Bifani P. J.;JAMA,1996

2. Mesure de la sensibilite du bacille tuberculeux aux drogues antibacillaires pour la methode des proportions;Canetti G.;Tubercle,1963

3. Centro Panamericano de Zoonosis (CEPANZO PAHO/WHO) Tuberculosis bacteriology. Technical note 11. 1988 Centro Panamericano de Zoonosis Buenos Aires Argentina (In Spanish.)

4. An outbreak of tuberculosis with accelerated progression among persons infected with the human immunodeficiency virus;Daley C. L.;N. Engl. J. Med.,1992

5. Molecular epidemiology of tuberculosis in Cuba, 1994–1995; comparison of IS6110 RFLP- and spoligotyping;Diaz R.;Int. J. Tuberc. Lung Dis.,1998

Cited by 43 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Genotyping methods and their contributions to the study of tuberculosis dynamic in Latin America;The Journal of Infection in Developing Countries;2023-11-12

2. Automated IS6110-based fingerprinting of Mycobacterium tuberculosis: Reaching unprecedented discriminatory power and versatility;PLOS ONE;2018-06-01

3. MDR-TB Outbreak among HIV-Negative Tunisian Patients followed during 11 Years;PLOS ONE;2016-04-28

4. Characterization of Microevolution Events in Mycobacterium tuberculosis Strains Involved in Recent Transmission Clusters;Journal of Clinical Microbiology;2011-09-21

5. Isolation of Mycobacterium tuberculosis Strains with a Silent Mutation inrpoBLeading to Potential Misassignment of Resistance Category;Journal of Clinical Microbiology;2011-05-11