Next-Generation-Sequencing-Based Hospital Outbreak Investigation Yields Insight into Klebsiella aerogenes Population Structure and Determinants of Carbapenem Resistance and Pathogenicity-Reference-Cited by-同舟云学术

Next-Generation-Sequencing-Based Hospital Outbreak Investigation Yields Insight into Klebsiella aerogenes Population Structure and Determinants of Carbapenem Resistance and Pathogenicity

Published:2019-06 Issue:6 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Malek Adel¹,McGlynn Kelly¹,Taffner Samantha¹,Fine Lynn²,Tesini Brenda³^ORCID,Wang Jun¹,Mostafa Heba¹,Petry Sharon¹,Perkins Archibald¹,Graman Paul³,Hardy Dwight¹⁴,Pecora Nicole¹

Affiliation:

1. Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, USA

2. Infection Prevention Program, University of Rochester Medical Center, Rochester, New York, USA

3. Department of Medicine, Infectious Diseases Division, University of Rochester Medical Center, Rochester, New York, USA

4. Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA

Abstract

Klebsiella aerogenes is a nosocomial pathogen associated with drug resistance and outbreaks in intensive care units. In a 5-month period in 2017, we experienced an increased incidence of cultures for carbapenem-resistant K. aerogenes (CR-KA) from an adult cardiothoracic intensive care unit (CICU) involving 15 patients.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02577-18

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