Failure of 1-β- d -Ribofuranosyl-1,2,4-Triazole-3-Carboxamide (Virazole, ICN 1229) to Stimulate Interferon-Reference-Cited by-同舟云学术

Failure of 1-β- d -Ribofuranosyl-1,2,4-Triazole-3-Carboxamide (Virazole, ICN 1229) to Stimulate Interferon

Published:1973-04 Issue:4 Volume:3 Page:534-535
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Allen Lois B.¹,Huffman John H.¹,Sidwell Robert W.¹

Affiliation:

1. Department of Virology, ICN Nucleic Acid Research Institute, Irvine, California 92664

Abstract

In cultured cells, Virazole failed to stimulate either interferon or a cellular resistance which continued in its absence. Serum from Virazole-treated mice likewise contained no demonstrable interferon.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.3.4.534

Reference12 articles.

1. Huffman J. H. R. W. Sidwell G. P. Khare J. T. NOTES 535

2. Witkowski L. B. Allen and R. K. Robins. 1973. In vitro

3. effect of 1-t-D-ribofuranosy1-1 2 4-triazole-3-carboxa

4. mide (Virazole ICN 1229) on deoxyribonucleic acid

5. and ribonucleic acid viruses. Antimicrob. Ag. Chemo

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