In Vitro Evaluation of a New Aminoglycoside Derivative of Kanamycin, BB-KA: a Comparison with Tobramycin and Gentamycin

Author:

Ries Kristen1,Levison Matthew E.1,Kaye Donald1

Affiliation:

1. Department of Medicine, Division of Infectious Diseases, The Medical College of Pennsylvania, and The Veterans Administration Hospital, Philadelphia, Pennsylvania 19129

Abstract

Against more than 90% of 200 bacterial strains tested in vitro, the inhibitory concentration of gentamicin and tobramycin was 3.1 μg/ml and that of BB-K 8, a new semisynthetic aminoglycoside derivative of kanamycin, was 6.3 μg/ml.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference3 articles.

1. BB-K 8, a new semi-synthetic aminoglycoside antibiotic;Kawaguchi H.;J. Antibiot. (Tokyo),1972

2. In vitro evaluation of tobramycin, a new aminoglycoside antibiotic;Levison M. E.;Antimicrob. Ag. Chemother.,1972

3. Microbiological evaluation of BB-K 8, a new semi-synthetic aminoglycoside;Price K. E.;J. Antibiot. (Tokyo),1972

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