Commensal Escherichia coli Aggravates Acute Necrotizing Pancreatitis through Targeting of Intestinal Epithelial Cells-Reference-Cited by-全球学者库

Commensal Escherichia coli Aggravates Acute Necrotizing Pancreatitis through Targeting of Intestinal Epithelial Cells

Published:2019-06-15 Issue:12 Volume:85 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Zheng Junyuan¹²,Lou Lihong³,Fan Junjie¹,Huang Chunlan¹,Mei Qixiang¹²,Wu Jianghong¹,Guo Yuecheng¹²,Lu Yingying¹,Wang Xingpeng¹²,Zeng Yue¹²

Affiliation:

1. Department of Gastroenterology, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

2. Shanghai Key Laboratory of Pancreatic Disease, Shanghai JiaoTong University School of Medicine, Shanghai, China

3. International Medical Care Center, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China

Abstract

This study describes the harmful potential of commensal E. coli in ANP, which has not been demonstrated in previous studies. Our work provides new insights into gut bacterium-ANP cross talk, suggesting that nonpathogenic commensals could also exhibit adverse effects in the context of diseases.

Funder

National Natural Science Foundation of China

Shanghai Jiao Tong University

Shanghai Hospital Development Center

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.00059-19

Reference32 articles.

1. The Crosstalk between Gut Inflammation and Gastrointestinal Disorders During Acute Pancreatitis