Abstract
A total of 48 strains of the soil bacterium Rhizobium japonicum were screened for their response to several widely used antibiotics. Over 60% of the strains were resistant to chloramphenicol, polymyxin B, and erythromycin, and 47% or more of the strains were resistant to neomycin and penicillin G, when tested by disk assay procedures. The most common grouping of resistances in strains was simultaneous resistance to tetracycline, penicillin G, neomycin, chloramphenicol, and streptomycin (25% of all strains tested). The occurrence of multiple drug resistance in a soil bacterium that is not a vertebrate pathogen suggests that chemotherapeutic use of antibiotics is not required for the development of multiple drug resistance.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Reference16 articles.
1. Origin of transferable drug-resistance factors in the Enterobacteriaceae;Anderson E. S.;Br. Med. J.,1965
2. Characterization of a transfer factor associated with drug resistance in Salmonella typhimurium;Anderson E. S.;Nature (London),1965
3. Anderson T. G. 1970. Testing of susceptibility to antimicrobial agents and assay of antimicrobial agents in body fluids p. 299-310. In J. E. Blair E. H. Lennette and J. P. Truant (ed.) Manual of clinical microbiology. The Williams & Wilkins Co. Baltimore.
4. Detection of resistance factors in fish pathogen Aeromonas liquifaciens;Aoki T.;J. Gen. Microbiol.,1971
5. Evolution of transferable antibiotic resistance in coliform bacteria from remote environments;Burt S. J.;Antimicrob. Agents Chemother.,1976
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