Production of FaeG, the Major Subunit of K88 Fimbriae, in Transgenic Tobacco Plants and Its Immunogenicity in Mice-Reference-Cited by-同舟云学术

Production of FaeG, the Major Subunit of K88 Fimbriae, in Transgenic Tobacco Plants and Its Immunogenicity in Mice

Published:2003-09 Issue:9 Volume:71 Page:5436-5439
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Huang Yahong¹²,Liang Wanqi²,Pan Aihu²,Zhou Zhiai³,Huang Cheng¹,Chen Jianxiu¹,Zhang Dabing²

Affiliation:

1. The Department of Biological Science and Technology, School of Life Science of Nanjing University, Nanjing

2. Shanghai Key Laboratory of Agricultural Genetics and Breeding, Agro-biotech Research Center, and Shanghai Key Laboratory of Agricultural Genetics Breeding

3. The Institute of Animal and Veterinary Sciences, Shanghai Academy of Agricultural Sciences, Shanghai, People's Republic of China

Abstract

ABSTRACT Transgenic tobacco plants stably expressing recombinant FaeG, which is the major subunit and adhesin of K88ad fimbriae, were obtained. Analysis of sera from immunized mice indicates that in mice, the immunogenicity induced by plant-derived FaeG protein is comparable to that generated with traditional approaches.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.71.9.5436-5439.2003

Reference32 articles.

1. Alexander T. J. L. 1994. Neonatal diarrhea in pigs p. 151-170. In C. L. Gyles (ed.) Escherichia coli in domestic animals and humans. CAB International Wallingford United Kingdom.

2. Arakawa, T., J. Yu, D. K. X. Chong, J. Hough, P. C. Engen, and W. H. R. Langridge. 1998. A plant-based cholera toxin B subunit-insulin fusion protein protects against the development of autoimmune diabetes. Nat. Biotechnol.16:934-938.

3. Bakker, D., C. E. M. Vader, B. Roosendaal, F. R. Mooi, B. Oudega, and F. K. de Graaf. 1991. Structure and function of periplasmic chaperone-like proteins involved in the biosynthesis of K88 and K99 fimbriae in enterotoxigenic Escherichia coli. Mol. Microbiol.5:875-886.

4. Identification of minor fimbrial subunits involved in biosynthesis of K88 fimbriae

5. Barman, N. N., and D. K. Sarma. 1999. Passive immunization of piglets against enterotoxigenic colibacillosis by vaccinating dams with K88ac pili bearing bacterins. Indian J. Exp. Biol.37:1132-1135.

Cited by 41 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Plant Molecular Farming for Developing Countries: Current Status and Future Perspectives;Concepts and Strategies in Plant Sciences;2023

2. Escherichia coli O157:H7 F9 Fimbriae Recognize Plant Xyloglucan and Elicit a Response in Arabidopsis thaliana;International Journal of Molecular Sciences;2020-12-19

3. Rice transcription factor MADS32 regulates floral patterning through interactions with multiple floral homeotic genes;Journal of Experimental Botany;2020-12-18

4. Superbugs, silver bullets, and new battlefields;Biodiversity and Biomedicine;2020

5. Prediction of vaccine candidates against Pseudomonas aeruginosa: An integrated genomics and proteomics approach;Genomics;2017-07