Affiliation:
1. Departments of Pediatrics and Medical Microbiology, College of Medicine, The Ohio State University, Columbus, Ohio 43210
Abstract
Forty-seven infants and children with a variety of infections including bacteremia, ethmoiditis, and periorbital cellulitis, soft tissue infection, pneumonia, and lymphadenitis were treated with intravenous cefamandole. The infections were due to
Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae
, and
Haemophilus influenzae
. The clinical response was prompt, and, with the exception of two cases who developed skin rash, significant side effects were not noted. In vitro cefamandole was very effective in inhibiting the growth of
H. influenzae
, including ampicillin-resistant isolates.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference2 articles.
1. Antibiotic sensitivity testing report of an international collaborative study;Ericsson H. M.;Acta Pathol. Microbiol. Scand. Sect. B,1971
2. Grove D. C. and W. A. Randall. 1955. Assay methods of antibiotics: a laboratory manual. Medical Encyclopedia New York.
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