Nosocomial Spread of an Unusual Methicillin-Resistant Staphylococcus aureus Clone That Is Sensitive to All Non-β-Lactam Antibiotics, Including Tobramycin-Reference-Cited by-同舟云学术

Nosocomial Spread of an Unusual Methicillin-Resistant Staphylococcus aureus Clone That Is Sensitive to All Non-β-Lactam Antibiotics, Including Tobramycin

Published:2001-02 Issue:2 Volume:39 Page:779-781
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Pournaras Spyros¹²,Slavakis Aris¹,Polyzou Aleka¹,Sofianou Danai¹,Maniatis Antonios N.²,Tsakris Athanassios³

Affiliation:

1. Department of Microbiology, Hippokration General Hospital,1 and

2. Department of Medical Microbiology, University of Thessalia, Larissa,2 Greece

3. Department of Microbiology, Medical School, Aristotle University of Thessaloniki,3 Thessaloniki, and

Abstract

ABSTRACT Between January and December 1999, in Hippokration General Hospital, Thessaloniki, Greece, a large proportion of the methicillin-resistant Staphylococcus aureus isolates (34.4%) exhibited susceptibility to virtually all alternative non-β-lactam antibiotics, including tobramycin. Twenty-five of them were selected randomly for further testing; all belonged to a unique genotype and were characterized as heterogeneously resistant to oxacillin. The aadD gene, encoding tobramycin resistance, failed to be amplified in all cases, indicating absence of the gene or the entire plasmid pUB110 from the mec DNA.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.39.2.779-781.2001

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