Clostridium carboxidivorans Strain P7T Recombinant Formate Dehydrogenase Catalyzes Reduction of CO 2 to Formate

Author:

Alissandratos Apostolos1,Kim Hye-Kyung1,Matthews Hayden1,Hennessy James E.1,Philbrook Amy1,Easton Christopher J.1

Affiliation:

1. CSIRO Biofuels Research Cluster, Research School of Chemistry, Australian National University, Canberra, Australia

Abstract

ABSTRACT Recombinant formate dehydrogenase from the acetogen Clostridium carboxidivorans strain P7 T , expressed in Escherichia coli , shows particular activity towards NADH-dependent carbon dioxide reduction to formate due to the relative binding affinities of the substrates and products. The enzyme retains activity over 2 days at 4°C under oxic conditions.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference19 articles.

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4. Total synthesis of acetate from CO2 by heterotrophic bacteria;Ljungdahl LG;Annu. Rev. Microbiol.,1969

5. Efficient conversion of CO2 to formic acid by formate dehydrogenase immobilized in a novel alginate-silica hybrid gel;Lu Y;Catal. Today,2006

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