Association between 16S-23S Internal Transcribed Spacer Sequence Groups of Mycobacterium avium Complex and Pulmonary Disease-Reference-Cited by-同舟云学术

Association between 16S-23S Internal Transcribed Spacer Sequence Groups of Mycobacterium avium Complex and Pulmonary Disease

Published:2008-08 Issue:8 Volume:46 Page:2790-2793
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Stout Jason E.¹,Hopkins Gregory W.²,McDonald Jay R.¹,Quinn Anita¹,Hamilton Carol D.¹,Reller L. Barth³,Frothingham Richard⁴

Affiliation:

1. Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina

2. Human Vaccine Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina

3. Division of Infectious Diseases and International Health, Department of Medicine, Department of Pathology, Duke University Medical Center, Durham, North Carolina

4. Human Vaccine Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina, and Infectious Diseases Section, Veterans Affairs Medical Center, Durham, North Carolina

Abstract

ABSTRACT Organisms within the Mycobacterium avium complex (MAC) may have differential virulence. We compared 33 subjects with MAC pulmonary disease to 75 subjects with a single positive culture without disease. M. avium isolates were significantly more likely to be associated with MAC pulmonary disease (odds ratio = 5.14, 95% confidence interval = 1.25 to 22.73) than M. intracellulare .

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00719-08

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