A Bacterial Cell-Based Assay To Study SARS-CoV-2 Protein-Protein Interactions-Reference-Cited by-同舟云学术

A Bacterial Cell-Based Assay To Study SARS-CoV-2 Protein-Protein Interactions

Published:2021-12-21 Issue:6 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Springstein Benjamin L.¹^ORCID,Deighan Padraig¹,Grabe Grzegorz J.¹,Hochschild Ann¹^ORCID

Affiliation:

1. Department of Microbiology, Harvard Medical School, Boston, Massachusetts, USA

Abstract

Understanding how virally encoded proteins interact with one another is essential in elucidating basic viral biology, providing a foundation for therapeutic discovery. Here, we describe the use of a versatile bacterium-based system to investigate the interactions of the protein set encoded by SARS-CoV-2, the virus responsible for the current COVID-19 pandemic.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.02936-21

Reference86 articles.

1. A pneumonia outbreak associated with a new coronavirus of probable bat origin

2. Characteristics of SARS-CoV-2 and COVID-19

3. Coronavirus biology and replication: implications for SARS-CoV-2

4. Type I and Type III Interferons – Induction, Signaling, Evasion, and Application to Combat COVID-19

5. A new coronavirus associated with human respiratory disease in China

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