Human Cytomegalovirus pUL11, a CD45 Ligand, Disrupts CD4 T Cell Control of Viral Spread in Epithelial Cells-Reference-Cited by-同舟云学术

Human Cytomegalovirus pUL11, a CD45 Ligand, Disrupts CD4 T Cell Control of Viral Spread in Epithelial Cells

Published:2022-12-20 Issue:6 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Osanyinlusi Samuel A.¹,Zischke Jasmin¹²,Jacobs Roland³,Weissinger Eva M.²⁴,Schulz Thomas F.¹²⁵^ORCID,Kay-Fedorov Penelope C.¹²^ORCID

Affiliation:

1. Institute of Virology, Hannover Medical School, Hannover, Germany

2. German Center for Infection Research (DZIF, TTU-IICH), Hannover-Braunschweig Site, Hannover, Germany

3. Department of Rheumatology and Clinical Immunology, Hannover Medical School, Hannover, Germany

4. Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

5. Cluster of Excellence 2155 RESIST, Hannover, Germany

Abstract

Human cytomegalovirus (HCMV) is adept at avoiding its host’s immune defenses, both by evading detection and by directly inhibiting immune cells. This can lead to a loss of control of the infection, and dangerous disease can result, particularly in cases in which an individual’s immune system is immature, weak, or suppressed.

Funder

Deutscher Akademischer Austauschdienst

Deutsches Zentrum für Infektionsforschung

Deutsche Forschungsgemeinschaft (DFG) under Germany’s Excellence Strategy - EXC 2155

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.02946-22

Reference78 articles.

1. Genetic content of wild-type human cytomegalovirus