Decreased Prevalence of Virulence Factors among Ciprofloxacin-Resistant Uropathogenic Escherichia coli Isolates

Author:

Drews S. J.12,Poutanen S. M.12,Mazzulli T.12,McGeer A. J.12,Sarabia A.3,Pong-Porter S.1,Rzayev Y.1,Willey B.1,Green K.1,Low D. E.12

Affiliation:

1. Toronto Medical Laboratories & Mount Sinai Hospital, Toronto, Ontario, Canada

2. University of Toronto, Toronto, Ontario, Canada

3. MDS Laboratories, Toronto, Ontario, Canada

Abstract

ABSTRACT Ciprofloxacin resistance was identified in 18% and 6% of consecutively collected, clinically significant urinary tract isolates of Escherichia coli from inpatients and outpatients, respectively. In comparison to ciprofloxacin-susceptible isolates, there were fewer resistant isolates that expressed beta-hemolysis (outpatient, 9% versus 87%, P < 0.0001; inpatient, 4% versus 76%, P < 0.0001) and that had a papEF genotype, genes encoding P fimbriae (outpatient, 30% versus 70%, P = 0.0004; inpatient, 26% versus 70%, P < 0.0001).

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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