Microbial Composition of the Human Nasopharynx Varies According to Influenza Virus Type and Vaccination Status-Reference-Cited by-同舟云学术

Microbial Composition of the Human Nasopharynx Varies According to Influenza Virus Type and Vaccination Status

Published:2019-08-27 Issue:4 Volume:10 Page:
ISSN:2161-2129
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Ding Tao¹,Song Timothy¹,Zhou Bin¹,Geber Adam¹,Ma Yixuan¹,Zhang Lingdi¹,Volk Michelle¹,Kapadia Shashi N.²,Jenkins Stephen G.³,Salvatore Mirella²^ORCID,Ghedin Elodie¹⁴^ORCID

Affiliation:

1. Center for Genomics & Systems Biology, Department of Biology, New York University, New York, New York, USA

2. Department of Medicine, Weill Cornell Medical College, New York, New York, USA

3. Department of Pathology, Weill Cornell Medical College, New York, New York, USA

4. Department of Epidemiology, College of Global Public Health, New York University, New York, New York, USA

Abstract

Our results suggest that there is a significant association between the composition of the microbiota in the nasopharynx and the influenza virus type causing the infection. We observe that vaccination status, especially in more senior individuals, also has an association with the microbial community profile. This indicates that vaccination against influenza, even when ineffective to prevent disease, could play a role in controlling secondary bacterial complications.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.01296-19

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