Molecular study of nosocomial nocardiosis outbreak involving heart transplant recipients

Author:

Exmelin L1,Malbruny B1,Vergnaud M1,Prosvost F1,Boiron P1,Morel C1

Affiliation:

1. Laboratoire de Microbiologie, Centre-Hospitalo-Universitaire Côte de Nacre, Caen, France.

Abstract

Randomly amplified polymorphic DNA analysis and rRNA gene restriction patterns (ribotyping) were compared as methods of investigating a nosocomial outbreak of nocardiosis involving three heart transplant recipients. No clear distinctions between three clinically related isolates and four unrelated strains were obtained by ribotyping. On the contrary, randomly amplified polymorphic DNA analysis with two selected primers, primers 2650 and DKU49, showed one pattern for the three related isolates and four patterns for the unrelated strains.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference28 articles.

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